| pubmed-article:12076992 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12076992 | lifeskim:mentions | umls-concept:C0028128 | lld:lifeskim |
| pubmed-article:12076992 | lifeskim:mentions | umls-concept:C0441712 | lld:lifeskim |
| pubmed-article:12076992 | pubmed:dateCreated | 2002-6-21 | lld:pubmed |
| pubmed-article:12076992 | pubmed:abstractText | Nitric oxide (NO) exerts numerous antiapoptotic effects on hepatocytes in settings of inflammation and tissue damage. These actions of NO are modulated by a variety of mechanisms under both physiologic and pathologic conditions. Nitric oxide inhibits cell death or apoptosis by modulation of heat shock proteins, S-nitrosylation of caspases at their catalytic site cysteine residue, triggering of the cGMP pathway, and prevention of mitochondrial dysfunction. Our preliminary studies also suggest that NO can modulate apoptosis-related genes in a manner consistent with an antiapoptotic effect. This review focuses on these molecular mechanisms of cytoprotection by NO. | lld:pubmed |
| pubmed-article:12076992 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12076992 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12076992 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12076992 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12076992 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12076992 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12076992 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12076992 | pubmed:month | May | lld:pubmed |
| pubmed-article:12076992 | pubmed:issn | 0077-8923 | lld:pubmed |
| pubmed-article:12076992 | pubmed:author | pubmed-author:BilliarTimoth... | lld:pubmed |
| pubmed-article:12076992 | pubmed:author | pubmed-author:VodovotzYoram... | lld:pubmed |
| pubmed-article:12076992 | pubmed:author | pubmed-author:KimPeter K... | lld:pubmed |
| pubmed-article:12076992 | pubmed:author | pubmed-author:WangYinnaY | lld:pubmed |
| pubmed-article:12076992 | pubmed:author | pubmed-author:ZamoraRubenR | lld:pubmed |
| pubmed-article:12076992 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12076992 | pubmed:volume | 962 | lld:pubmed |
| pubmed-article:12076992 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12076992 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12076992 | pubmed:pagination | 415-22 | lld:pubmed |
| pubmed-article:12076992 | pubmed:dateRevised | 2005-11-16 | lld:pubmed |
| pubmed-article:12076992 | pubmed:meshHeading | pubmed-meshheading:12076992... | lld:pubmed |
| pubmed-article:12076992 | pubmed:meshHeading | pubmed-meshheading:12076992... | lld:pubmed |
| pubmed-article:12076992 | pubmed:meshHeading | pubmed-meshheading:12076992... | lld:pubmed |
| pubmed-article:12076992 | pubmed:meshHeading | pubmed-meshheading:12076992... | lld:pubmed |
| pubmed-article:12076992 | pubmed:meshHeading | pubmed-meshheading:12076992... | lld:pubmed |
| pubmed-article:12076992 | pubmed:meshHeading | pubmed-meshheading:12076992... | lld:pubmed |
| pubmed-article:12076992 | pubmed:meshHeading | pubmed-meshheading:12076992... | lld:pubmed |
| pubmed-article:12076992 | pubmed:meshHeading | pubmed-meshheading:12076992... | lld:pubmed |
| pubmed-article:12076992 | pubmed:meshHeading | pubmed-meshheading:12076992... | lld:pubmed |
| pubmed-article:12076992 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12076992 | pubmed:articleTitle | Mechanisms of hepatoprotection by nitric oxide. | lld:pubmed |
| pubmed-article:12076992 | pubmed:affiliation | Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. | lld:pubmed |
| pubmed-article:12076992 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12076992 | pubmed:publicationType | Review | lld:pubmed |
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