Source:http://linkedlifedata.com/resource/pubmed/id/12075862
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2002-6-21
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pubmed:abstractText |
Alterations of G proteins have been implicated in major psychiatric illnesses. A C825T polymorphism of a gene encoding the beta3 subunit of heterotrimeric G proteins (GNB3) was reported to be associated with several pathological conditions, such as hypertension and depressive disorder. We examined whether this polymorphism is associated with functional psychoses in a Japanese sample of 370 schizophrenics, 164 bipolars, 68 depressive patients, and 198 controls. We obtained no evidence for an association of the polymorphism with any diagnostic group.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0300-9564
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
213-8
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12075862-Adult,
pubmed-meshheading:12075862-Bipolar Disorder,
pubmed-meshheading:12075862-Depressive Disorder, Major,
pubmed-meshheading:12075862-Female,
pubmed-meshheading:12075862-Gene Frequency,
pubmed-meshheading:12075862-Genetic Predisposition to Disease,
pubmed-meshheading:12075862-Genotype,
pubmed-meshheading:12075862-Heterotrimeric GTP-Binding Proteins,
pubmed-meshheading:12075862-Humans,
pubmed-meshheading:12075862-Japan,
pubmed-meshheading:12075862-Male,
pubmed-meshheading:12075862-Middle Aged,
pubmed-meshheading:12075862-Polymorphism, Genetic,
pubmed-meshheading:12075862-Schizophrenia
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pubmed:year |
2002
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pubmed:articleTitle |
Association study of C825T polymorphism of the G-protein b3 subunit gene with schizophrenia and mood disorders.
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pubmed:affiliation |
Department of Psychiatry and Genome Research Center, Teikyo University School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article
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