Linked Life Data

12074619

Source:http://linkedlifedata.com/resource/pubmed/id/12074619

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-6-20
pubmed:abstractText
This study assessed the role of a novel fibrin sealant (Vivostat in adhesion reduction after flexor tendon surgery. The deep flexor tendons of the 2nd and 4th digits of the left paw of 20 rabbits were exposed and a standard partial injury was performed on each. The rabbits were randomized to either immediate post-injury treatment with Vivostat or no treatment. In each case active movement of the 2nd digit was prevented while the 4th digit was allowed to move normally. The two groups were assessed at 14 days for adhesion formation with a tensiometer. The right paw acted as the unoperated control. Results showed that there was no significant difference in the force needed to remove the tendon from its sheath when comparing the two Vivostat((R))-treated groups to the unoperated controls. There was, however, a highly significant difference in this force between the non-Vivostat-treated groups and the unoperated controls. This suggests a beneficial effect of Vivostat in reducing post surgical tendon adhesion formation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0266-7681
pubmed:author
pubmed:copyrightInfo
Copyright 2002 The British Society for Surgery of the Hand.
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
278-82
pubmed:dateRevised
2009-6-8
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
The role of human-derived fibrin sealant in the reduction of postoperative flexor tendon adhesion formation in rabbits.
pubmed:affiliation
RAFT Institute of Plastic Surgery, Mount Vernon Hospital, Northwood, Middlesex, UK. martine.jones@virgin.net
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't