Source:http://linkedlifedata.com/resource/pubmed/id/12069729
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
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pubmed:dateCreated |
2002-6-18
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pubmed:abstractText |
The relative synonymous codon use frequency of 135 MHC genes from four mammal species (Homo sapiens, Pan troglodyte, Macaca mulanta and Rattus norvegicus) is analyzed using a hierarchical cluster method. The result suggests that gene function is the dominant factor that determines codon usage bias, while species is a minor factor that determines further difference in codon usage bias for genes with similar functions. The conclusion may be useful in gene classification and gene function prediction.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0303-2647
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
199-207
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12069729-Animals,
pubmed-meshheading:12069729-Cluster Analysis,
pubmed-meshheading:12069729-Codon,
pubmed-meshheading:12069729-Macaca mulatta,
pubmed-meshheading:12069729-Major Histocompatibility Complex,
pubmed-meshheading:12069729-Rats,
pubmed-meshheading:12069729-Species Specificity
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pubmed:articleTitle |
Cluster analysis of the codon use frequency of MHC genes from different species.
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pubmed:affiliation |
Chien-Shiung Wu Laboratory, Southeast University, 210096 Jiangsu Province, Nanjing, People's Republic of China. jmma@seu.edu.cn
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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