Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2002-6-14
pubmed:abstractText
Over the last decade GH replacement therapy for adults has progressed in status from research study to a mainstream clinical indication. An area ripe for further research, however, is the difference between adults who developed GHD before and after completion of growth and puberty. That differences exist, not only in aetiology, but also in phenotype and response to GH therapy is clear. However, whether these differences are intrinsic to the timing of onset of GHD, or related to secondary factors including the method of assessment or dose of GH employed is uncertain. This chapter discusses the current state of knowledge in this area and poses further questions, not only for the researcher attempting to understand the mechanisms underlying these differences, but also for the physician seeking to ameliorate the impact of GHD in patients who acquired GHD in childhood.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1521-690X
pubmed:author
pubmed:copyrightInfo
Copyright 2002 Elsevier Science Ltd.
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
209-24
pubmed:dateRevised
2006-10-30
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Childhood-onset growth hormone (GH) deficiency in adult life.
pubmed:affiliation
Department of Endocrinology, Christie Hospital, Manchester, UK.
pubmed:publicationType
Journal Article, Review