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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2002-6-13
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pubmed:abstractText |
Fludarabine, 9-beta-D-arabinofuranosyl-2-fluoroadenine, is an adenine nucleoside analogue that has significant activity in hematological malignancies and has shown promising activity in combination with radiation in preclinical solid tumor models. In this framework, we designed two phase I trials (one conducted at M.D. Anderson Cancer Center in Houston, and the other conducted in two Belgian hospitals) exploring concurrent fludarabine and radiotherapy in patients with intermediate to locally advanced head and neck squamous cell carcinomas (HNSCC).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0167-8140
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pubmed:author |
pubmed-author:AngK KianKK,
pubmed-author:BeauduinMarcM,
pubmed-author:GardenAdam SAS,
pubmed-author:GrégoireVincentV,
pubmed-author:HamoirMarcM,
pubmed-author:HittelmanWalter NWN,
pubmed-author:HumbletYvesY,
pubmed-author:KhuriFadlo RFR,
pubmed-author:MilasLukaL,
pubmed-author:MitineCarineC,
pubmed-author:RosierJean-FrançoisJF,
pubmed-author:ScallietPierreP
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pubmed:issnType |
Print
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
187-93
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12063008-Adult,
pubmed-meshheading:12063008-Aged,
pubmed-meshheading:12063008-Aged, 80 and over,
pubmed-meshheading:12063008-Antineoplastic Agents,
pubmed-meshheading:12063008-Carcinoma, Squamous Cell,
pubmed-meshheading:12063008-Combined Modality Therapy,
pubmed-meshheading:12063008-Female,
pubmed-meshheading:12063008-Humans,
pubmed-meshheading:12063008-Male,
pubmed-meshheading:12063008-Middle Aged,
pubmed-meshheading:12063008-Mouth Neoplasms,
pubmed-meshheading:12063008-Otorhinolaryngologic Neoplasms,
pubmed-meshheading:12063008-Radiation Injuries,
pubmed-meshheading:12063008-Vidarabine
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pubmed:year |
2002
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pubmed:articleTitle |
A phase I study of fludarabine combined with radiotherapy in patients with intermediate to locally advanced head and neck squamous cell carcinoma.
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pubmed:affiliation |
Department of Radiation Oncology, Université Catholique de Louvain, St-Luc University Hospital, 10 Avenue Hippocrate, Brussels, Belgium.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase I
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