Source:http://linkedlifedata.com/resource/pubmed/id/12062170
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2002-6-13
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pubmed:abstractText |
Protein kinase CK2 (formerly known as casein kinase 2) is a serine/threonine protein kinase whose functions have been under investigation for over three decades, leading to the recognition that it interacts with several signaling pathways. Recent demonstrations of signal-mediated dynamic localization of CK2 and the identification of new signaling targets for it have converged to indicate an unexpected function for this protein kinase: cell survival. Here, we summarize our emerging knowledge about how CK2 might participate in the transduction of survival signals.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0962-8924
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
226-30
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12062170-Animals,
pubmed-meshheading:12062170-Caenorhabditis elegans,
pubmed-meshheading:12062170-Casein Kinase II,
pubmed-meshheading:12062170-Cell Division,
pubmed-meshheading:12062170-Cell Survival,
pubmed-meshheading:12062170-Crystallography, X-Ray,
pubmed-meshheading:12062170-Humans,
pubmed-meshheading:12062170-Models, Biological,
pubmed-meshheading:12062170-Models, Molecular,
pubmed-meshheading:12062170-Neoplasms,
pubmed-meshheading:12062170-Protein-Serine-Threonine Kinases,
pubmed-meshheading:12062170-Saccharomyces cerevisiae,
pubmed-meshheading:12062170-Signal Transduction
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pubmed:year |
2002
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pubmed:articleTitle |
Joining the cell survival squad: an emerging role for protein kinase CK2.
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pubmed:affiliation |
Cellular and Molecular Biochemistry Research Laboratory (151), Minneapolis Veterans Affairs Medical Center, Dept Laboratory Medicine and Pathology, MN 55417, USA. ahmedk@umn.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Review,
Research Support, Non-U.S. Gov't
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