Linked Life Data

12060634

Source:http://linkedlifedata.com/resource/pubmed/id/12060634

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2002-6-12
pubmed:abstractText
Aberrant DNA methylation of promoter-associated CpG islands is an epigenetic DNA modification observed in acute leukemias that in certain cases has been associated with a poor prognosis and increased relapse rates. To study the role of DNA methylation in relapse mechanisms in acute lymphocytic leukemia (ALL), we have compared the methylation status of five genes at the time of initial presentation and at first relapse in 25 adult patients with ALL.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/CDKN2B protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Cell Cycle Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor..., http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm, http://linkedlifedata.com/resource/pubmed/chemical/DNA Primers, http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Estrogen, http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins, http://linkedlifedata.com/resource/pubmed/chemical/tumor suppressor protein p73
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1078-0432
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1897-903
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:12060634-Adolescent, pubmed-meshheading:12060634-Adult, pubmed-meshheading:12060634-Aged, pubmed-meshheading:12060634-Bone Marrow, pubmed-meshheading:12060634-Cell Cycle Proteins, pubmed-meshheading:12060634-CpG Islands, pubmed-meshheading:12060634-Cyclin-Dependent Kinase Inhibitor p15, pubmed-meshheading:12060634-DNA, Neoplasm, pubmed-meshheading:12060634-DNA Methylation, pubmed-meshheading:12060634-DNA Primers, pubmed-meshheading:12060634-DNA-Binding Proteins, pubmed-meshheading:12060634-Female, pubmed-meshheading:12060634-Genes, MDR, pubmed-meshheading:12060634-Genes, Tumor Suppressor, pubmed-meshheading:12060634-Genes, p16, pubmed-meshheading:12060634-Humans, pubmed-meshheading:12060634-Immunoenzyme Techniques, pubmed-meshheading:12060634-Male, pubmed-meshheading:12060634-Middle Aged, pubmed-meshheading:12060634-Neoplasm Proteins, pubmed-meshheading:12060634-Nuclear Proteins, pubmed-meshheading:12060634-Polymerase Chain Reaction, pubmed-meshheading:12060634-Precursor Cell Lymphoblastic Leukemia-Lymphoma, pubmed-meshheading:12060634-Receptors, Estrogen, pubmed-meshheading:12060634-Sensitivity and Specificity, pubmed-meshheading:12060634-Transcription Factors, pubmed-meshheading:12060634-Tumor Markers, Biological, pubmed-meshheading:12060634-Tumor Suppressor Proteins
pubmed:year
2002
pubmed:articleTitle
DNA methylation patterns at relapse in adult acute lymphocytic leukemia.
pubmed:affiliation
Department of Leukemia, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA. ggarciam@mdanderson.org
pubmed:publicationType
Journal Article