Linked Life Data

12056575

Source:http://linkedlifedata.com/resource/pubmed/id/12056575

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-6-11
pubmed:abstractText
To examine the left temporal scalp area reductions of P300 amplitude, event-related potentials (ERPs) during a standard oddball task were recorded in 57 schizophrenic patients and 33 normal controls. The P300 amplitude at T3 was not significantly smaller than that at T4 in schizophrenic patients. In the ANOVA analysis of the P300 peak amplitude and PCA factor scores, significant lateral topographical differences in P300 were not present between patients and controls. However, in schizophrenia, patients in the low T3 P300 group were older and consuming higher doses of antipsychotic medicine than those in the high T3 P300 group, and they had relatively low P300 amplitudes and significantly delayed P300 latency, compared with those in the high T3 P300 group. These findings suggested that although the reduction in the left temporal P300 amplitude did not necessarily exist in schizophrenic patients, it may be associated with the severity of the disease process and/or impairment of cognitive function.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0940-1334
pubmed:author
pubmed:issnType
Print
pubmed:volume
252
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-7
pubmed:dateRevised
2009-5-11
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
P300 amplitude over temporal regions in schizophrenia.
pubmed:affiliation
Department of Neuropsychiatry, Faculty of Medicine, University of Tokyo, Japan. iwanami-tky@umin.ac.jp
pubmed:publicationType
Journal Article, Comparative Study