12056509

Source:http://linkedlifedata.com/resource/pubmed/id/12056509

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0006100, umls-concept:C0007966, umls-concept:C0018557, umls-concept:C0021753, umls-concept:C0025962, umls-concept:C0037494, umls-concept:C0064325, umls-concept:C0205263, umls-concept:C0333348, umls-concept:C0392747, umls-concept:C0443172, umls-concept:C1280500, umls-concept:C1553454
pubmed:issue	5
pubmed:dateCreated	2002-6-11
pubmed:abstractText	The purpose of this study was to assess the efficacy of topically applied ketoprofen lysine salt (KLS), a cyclooxygenase inhibitor, against the inflammatory changes induced by interleukin-1beta (IL-1beta) and bradykinin (BK) in hamster cheek pouch microcirculation. In addition, we characterised the pharmacological regulation of IL-1beta activity in this model.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9508160
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Inflammatory Agents..., http://linkedlifedata.com/resource/pubmed/chemical/Bradykinin, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1, http://linkedlifedata.com/resource/pubmed/chemical/Ketoprofen, http://linkedlifedata.com/resource/pubmed/chemical/Lysine, http://linkedlifedata.com/resource/pubmed/chemical/Platelet Membrane Glycoproteins, http://linkedlifedata.com/resource/pubmed/chemical/Protein Synthesis Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Bradykinin B2, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Bradykinin, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, G-Protein-Coupled, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-1, http://linkedlifedata.com/resource/pubmed/chemical/ketoprofen lysine, http://linkedlifedata.com/resource/pubmed/chemical/platelet activating factor receptor
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	1023-3830
pubmed:author	pubmed-author:BertugliaSS, pubmed-author:DaffonchioLL, pubmed-author:NovelliniRR
pubmed:issnType	Print
pubmed:volume	51
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	223-8
pubmed:dateRevised	2005-11-17
pubmed:meshHeading	pubmed-meshheading:12056509-Animals, pubmed-meshheading:12056509-Anti-Inflammatory Agents, Non-Steroidal, pubmed-meshheading:12056509-Bradykinin, pubmed-meshheading:12056509-Capillary Permeability, pubmed-meshheading:12056509-Cricetinae, pubmed-meshheading:12056509-Humans, pubmed-meshheading:12056509-Inflammation, pubmed-meshheading:12056509-Interleukin-1, pubmed-meshheading:12056509-Ketoprofen, pubmed-meshheading:12056509-Lysine, pubmed-meshheading:12056509-Male, pubmed-meshheading:12056509-Mesocricetus, pubmed-meshheading:12056509-Microcirculation, pubmed-meshheading:12056509-Mouth Mucosa, pubmed-meshheading:12056509-Platelet Membrane Glycoproteins, pubmed-meshheading:12056509-Protein Synthesis Inhibitors, pubmed-meshheading:12056509-Receptor, Bradykinin B2, pubmed-meshheading:12056509-Receptors, Bradykinin, pubmed-meshheading:12056509-Receptors, Cell Surface, pubmed-meshheading:12056509-Receptors, G-Protein-Coupled, pubmed-meshheading:12056509-Receptors, Interleukin-1
pubmed:year	2002
pubmed:articleTitle	Protective effect of ketoprofen lysine salt on interleukin-1beta and bradykinin induced inflammatory changes in hamster cheek pouch microcirculation.
pubmed:affiliation	Dompé s.p.a., Medical Department, Milano, Italy. daffonchio.luisa@dompe.it
pubmed:publicationType	Journal Article