Linked Life Data

12054004

Source:http://linkedlifedata.com/resource/pubmed/id/12054004

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2002-6-10
pubmed:abstractText
The susceptibility of Psammomys obesus (sand rat) and Meriones tristrami (Tristram's jird) to Neospora caninum was investigated by subcutaneous (s.c.) and intraperitoneal (i.p.) inoculation of 10-fold doses of culture-derived tachyzoites. Groups of 5 animals were inoculated with doses of 10-10(7) parasites via each route of inoculation. All but 2 of the sand rats inoculated with doses of 10-10(4) parasites succumbed to the infection by 7-18 days postinfection. All jirds inoculated with 10(7) tachyzoites succumbed by 5-16 days postinfection and those inoculated with 10(6) tachyzoites by 9-25 days. A considerable proportion of the jirds inoculated with 10-10(5) tachyzoites survived. Fibrinous peritonitis with ascites containing numerous tachyzoites was observed in the i.p.-inoculated sand rats and jirds that succumbed to the infection. In the jirds, tachyzoites were also found in pleural exudate. A considerable number (42.8%) of the jirds inoculated s.c. or i.p. exhibited neuromuscular symptoms, expressed in ataxia, head tilt, circling movement, and posterior paralysis. Seven successive passage of tachyzoites were achieved in sand rats with doses of 10(5) parasites and in jirds with doses of 10(7) parasites. All surviving jirds became seroconverted and were immune to lethal challenge.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-3395
pubmed:author
pubmed:issnType
Print
pubmed:volume
88
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
314-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Susceptibility of Psammomys obesus and Meriones tristrami to tachyzoites of Neospora caninum.
pubmed:affiliation
Division of Parasitology, The Kimron Veterinary Institute, Bet Dagan, Israel. epipa_vs@netvision.net.il
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't