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rdf:type |
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lifeskim:mentions |
umls-concept:C0007873,
umls-concept:C0013081,
umls-concept:C0031437,
umls-concept:C0205282,
umls-concept:C0332281,
umls-concept:C0580822,
umls-concept:C0598086,
umls-concept:C0598388,
umls-concept:C1415887,
umls-concept:C1419040,
umls-concept:C1420433,
umls-concept:C1424666,
umls-concept:C1510411,
umls-concept:C1547300,
umls-concept:C1548760,
umls-concept:C1550594
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pubmed:issue |
3
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pubmed:dateCreated |
2002-6-7
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pubmed:abstractText |
p27Kip1 (p27) is a member of the cyclin-dependent kinase inhibitor family. The level of p27 protein expression decreases during tumor development and progression in some epithelial tumors. To identify the potential implications of the p27 gene in the development of cervical carcinoma and explore the clinical importance of change in gene expression, we assessed the level of p27 protein in precancerous lesions and carcinomas of the cervix.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0090-8258
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
524-8
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:12051885-Adult,
pubmed-meshheading:12051885-Aged,
pubmed-meshheading:12051885-Aged, 80 and over,
pubmed-meshheading:12051885-Carcinoma, Squamous Cell,
pubmed-meshheading:12051885-Cell Cycle Proteins,
pubmed-meshheading:12051885-Cell Transformation, Neoplastic,
pubmed-meshheading:12051885-Cervical Intraepithelial Neoplasia,
pubmed-meshheading:12051885-Cervix Uteri,
pubmed-meshheading:12051885-Cyclin-Dependent Kinase Inhibitor p27,
pubmed-meshheading:12051885-Down-Regulation,
pubmed-meshheading:12051885-Epithelial Cells,
pubmed-meshheading:12051885-Female,
pubmed-meshheading:12051885-Humans,
pubmed-meshheading:12051885-Immunohistochemistry,
pubmed-meshheading:12051885-Middle Aged,
pubmed-meshheading:12051885-Neoplasm Invasiveness,
pubmed-meshheading:12051885-Prognosis,
pubmed-meshheading:12051885-Tumor Suppressor Proteins,
pubmed-meshheading:12051885-Uterine Cervical Neoplasms
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pubmed:year |
2002
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pubmed:articleTitle |
Down-regulation of p27 is associated with malignant transformation and aggressive phenotype of cervical neoplasms.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan. m002057@ms.skh.org.tw
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pubmed:publicationType |
Journal Article
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