Source:http://linkedlifedata.com/resource/pubmed/id/12051390
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2002-6-7
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| pubmed:abstractText |
Giant cell (temporal) arteritis (GCA) and polymyalgia rheumatica (PMR) are different but overlapping diseases of unknown etiology affecting the elderly. Corticotropin-releasing hormone (CRH) helps to regulate the immune response and maintain homeostasis during inflammatory stress. CRH promoter region polymorphisms in the 5'regulatory region of the CRH gene have been described. To investigate the possible implications of the CRH promoter polymorphisms in PMR and GCA susceptibility we have examined a series of patients with these conditions.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0392-856X
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
20
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
133-8
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| pubmed:dateRevised |
2008-11-21
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| pubmed:meshHeading |
pubmed-meshheading:12051390-Aged,
pubmed-meshheading:12051390-Alleles,
pubmed-meshheading:12051390-Amino Acid Sequence,
pubmed-meshheading:12051390-Corticotropin-Releasing Hormone,
pubmed-meshheading:12051390-Female,
pubmed-meshheading:12051390-Gene Frequency,
pubmed-meshheading:12051390-Giant Cell Arteritis,
pubmed-meshheading:12051390-Humans,
pubmed-meshheading:12051390-Male,
pubmed-meshheading:12051390-Middle Aged,
pubmed-meshheading:12051390-Polymorphism, Genetic,
pubmed-meshheading:12051390-Polymyalgia Rheumatica,
pubmed-meshheading:12051390-Promoter Regions, Genetic
|
| pubmed:articleTitle |
Corticotropin releasing hormone promoter polymorphisms in giant cell arteritis and polymyalgia rheumatica.
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| pubmed:affiliation |
Division of Rheumatology, Hospital Xeral-Calde, Lugo, Spain. miguelaggay@hotmail.com
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| pubmed:publicationType |
Journal Article
|