Source:http://linkedlifedata.com/resource/pubmed/id/12048222
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2002-6-5
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pubmed:abstractText |
The authors investigated the cancer risk of patients hospitalized for depression in a nationwide Danish cohort study. All 89,491 adults in Denmark who had been admitted to a hospital with depression, as defined in the International Classification of Diseases, Eighth Revision, between 1969 and 1993 were identified. There were 1,117,006 person-years of follow-up. Incidence rates of all cancers and of site-specific cancers were compared with national incidence rates for first primary cancers, with data being adjusted for sex, age, and calendar time. A total of 9,922 cases of cancer were diagnosed in the cohort, with 9,434.6 having been expected; this yielded a standardized incidence ratio of 1.05 (95% confidence interval (CI): 1.03, 1.07). The risk of cancer was increased for the first year after hospital admission, with brain cancer especially occurring more frequently than expected. When the first year of follow-up was excluded, the increase was attributable mainly to an increased risk of tobacco-related cancers: Standardized incidence ratios for non-tobacco-related cancers were 1.00 (95% CI: 0.97, 1.03) after 1-9 years of follow-up and 0.99 (95% CI: 0.95, 1.02) after 10 or more years of follow-up. These data provide no support for the hypothesis that depression independently increases risk of cancer, but they emphasize the deleterious effect that depression can have on lifestyle factors.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0002-9262
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
155
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1088-95
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12048222-Adult,
pubmed-meshheading:12048222-Affective Disorders, Psychotic,
pubmed-meshheading:12048222-Cohort Studies,
pubmed-meshheading:12048222-Denmark,
pubmed-meshheading:12048222-Female,
pubmed-meshheading:12048222-Hospitalization,
pubmed-meshheading:12048222-Humans,
pubmed-meshheading:12048222-Male,
pubmed-meshheading:12048222-Middle Aged,
pubmed-meshheading:12048222-Neoplasms,
pubmed-meshheading:12048222-Registries,
pubmed-meshheading:12048222-Risk Factors,
pubmed-meshheading:12048222-Smoking
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pubmed:year |
2002
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pubmed:articleTitle |
Depression and cancer risk: a register-based study of patients hospitalized with affective disorders, Denmark, 1969-1993.
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pubmed:affiliation |
Danish Cancer Society, Institute of Cancer Epidemiology, DK-2100 Copenhagen, Denmark. sanne@cancer.dk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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