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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1976-3-20
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pubmed:abstractText |
Two normal diploid control cell lines and a heteroploid malignant transformed cell line from B(a)P treated hamster embryo cell cultures were established. The 14-month-old B(a)P transformed cell line grew 8-times faster than the 20-month-old control cell line. The control cell line showed normal diploid chromosome complement in 93% cells and heteroploidy in 7% cells while B(a)P treated line showed 83% heteroploid cells and only 17% diploid cells. This is the first report on the establishment of diploid hamster cell cultures grown for extended period.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
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pubmed:issn |
0014-4754
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
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pubmed:volume |
31
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1215-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1204748-Animals,
pubmed-meshheading:1204748-Benzopyrenes,
pubmed-meshheading:1204748-Cell Line,
pubmed-meshheading:1204748-Cell Transformation, Neoplastic,
pubmed-meshheading:1204748-Chromosomes,
pubmed-meshheading:1204748-Cricetinae,
pubmed-meshheading:1204748-Diploidy,
pubmed-meshheading:1204748-Mitosis,
pubmed-meshheading:1204748-Polyploidy
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pubmed:year |
1975
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pubmed:articleTitle |
Establishment of normal diploid and malignant heteroploid cell lines from non-treated and benzo(a)pyrene treated hamster embryo cell cultures.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, Non-P.H.S.
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