| pubmed-article:12046991 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12046991 | lifeskim:mentions | umls-concept:C0014467 | lld:lifeskim |
| pubmed-article:12046991 | lifeskim:mentions | umls-concept:C0079717 | lld:lifeskim |
| pubmed-article:12046991 | lifeskim:mentions | umls-concept:C0332448 | lld:lifeskim |
| pubmed-article:12046991 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:12046991 | lifeskim:mentions | umls-concept:C0527189 | lld:lifeskim |
| pubmed-article:12046991 | lifeskim:mentions | umls-concept:C1334146 | lld:lifeskim |
| pubmed-article:12046991 | lifeskim:mentions | umls-concept:C1366562 | lld:lifeskim |
| pubmed-article:12046991 | lifeskim:mentions | umls-concept:C1706439 | lld:lifeskim |
| pubmed-article:12046991 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:12046991 | lifeskim:mentions | umls-concept:C0021469 | lld:lifeskim |
| pubmed-article:12046991 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:12046991 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:12046991 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:12046991 | pubmed:dateCreated | 2002-6-5 | lld:pubmed |
| pubmed-article:12046991 | pubmed:abstractText | The inhibitory effect of olopatadine, a new antiallergic drug, on antigen-induced eosinophil infiltration and its mechanisms were examined using the local sensitized rat allergic rhinitis model and isolated IL-5-stimulated rat peritoneal eosinophils. Olopatadine dose-dependently inhibited antigen-induced eosinophil infiltration in the nasal mucosa. Olopatadine dose-dependently repressed the IL-5-induced expressions of CD11a/CD18 (LFA-1) and CD11b/CD18 (Mac-1) on rat peritoneal eosinophils. However, olopatadine had no effect on IL-5-induced CD49d/CD29 (VLA-4) expression. These results suggest that olopatadine may inhibit antigen-induced eosinophil infiltration through repression of LFA-1 and Mac-1 expression. | lld:pubmed |
| pubmed-article:12046991 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12046991 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12046991 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12046991 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12046991 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12046991 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12046991 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12046991 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12046991 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12046991 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12046991 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12046991 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12046991 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12046991 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:12046991 | pubmed:issn | 0021-5198 | lld:pubmed |
| pubmed-article:12046991 | pubmed:author | pubmed-author:FukuishiNobuy... | lld:pubmed |
| pubmed-article:12046991 | pubmed:author | pubmed-author:MatsuhisaMoto... | lld:pubmed |
| pubmed-article:12046991 | pubmed:author | pubmed-author:ShimonoTakesh... | lld:pubmed |
| pubmed-article:12046991 | pubmed:author | pubmed-author:MurataNobutos... | lld:pubmed |
| pubmed-article:12046991 | pubmed:author | pubmed-author:IwanagaMariM | lld:pubmed |
| pubmed-article:12046991 | pubmed:author | pubmed-author:SagaraHidenor... | lld:pubmed |
| pubmed-article:12046991 | pubmed:author | pubmed-author:MatsuiNobuaki... | lld:pubmed |
| pubmed-article:12046991 | pubmed:author | pubmed-author:AkagiMasaakiM | lld:pubmed |
| pubmed-article:12046991 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12046991 | pubmed:volume | 88 | lld:pubmed |
| pubmed-article:12046991 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12046991 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12046991 | pubmed:pagination | 463-6 | lld:pubmed |
| pubmed-article:12046991 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:12046991 | pubmed:meshHeading | pubmed-meshheading:12046991... | lld:pubmed |
| pubmed-article:12046991 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12046991 | pubmed:articleTitle | Inhibitory effect of olopatadine on antigen-induced eosinophil infiltration and the LFA-1 and Mac-1 expression in eosinophils. | lld:pubmed |
| pubmed-article:12046991 | pubmed:affiliation | Department of Pharmacology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan. | lld:pubmed |
| pubmed-article:12046991 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12046991 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:12046991 | pubmed:publicationType | In Vitro | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:12046991 | lld:pubmed |
