Source:http://linkedlifedata.com/resource/umls/id/C0079717
MSH: An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (ANTIGENS, CD18) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-CELLS; B-CELLS; and GRANULOCYTES. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.,NCI: Integrin alphaL/beta2 is a protein complex comprised of a heterodimer of integrin alphaL and integrin beta2. This complex is involved in leukocyte adhesion, cytolysis, helper T-cell interactions, and antibody-dependent killing by natural killer cells and granulocytes.