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rdf:type |
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lifeskim:mentions |
umls-concept:C0007600,
umls-concept:C0007634,
umls-concept:C0010656,
umls-concept:C0035820,
umls-concept:C0079419,
umls-concept:C0079904,
umls-concept:C0086418,
umls-concept:C0162638,
umls-concept:C0162772,
umls-concept:C0205263,
umls-concept:C0278701,
umls-concept:C0376515,
umls-concept:C0392747,
umls-concept:C0670957,
umls-concept:C0796126,
umls-concept:C1510779,
umls-concept:C2697827
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pubmed:issue |
3
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pubmed:dateCreated |
2002-6-4
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pubmed:abstractText |
To identify whether JTE-522 can induce apoptosis in AGS cells and ROS also involved in the process, and to investigate the changes in NF-kB, p53, bcl-2 and caspase in the apoptosis process.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/4-(4-cyclohexyl-2-methyloxazol-5-yl)...,
http://linkedlifedata.com/resource/pubmed/chemical/Benzenesulfonates,
http://linkedlifedata.com/resource/pubmed/chemical/Caspases,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/I-kappa B Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappaB inhibitor alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Oxazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-bcl-2,
http://linkedlifedata.com/resource/pubmed/chemical/Reactive Oxygen Species,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p53
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1007-9327
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
431-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12046064-Adenocarcinoma,
pubmed-meshheading:12046064-Apoptosis,
pubmed-meshheading:12046064-Benzenesulfonates,
pubmed-meshheading:12046064-Caspases,
pubmed-meshheading:12046064-Cell Division,
pubmed-meshheading:12046064-DNA-Binding Proteins,
pubmed-meshheading:12046064-Humans,
pubmed-meshheading:12046064-I-kappa B Proteins,
pubmed-meshheading:12046064-NF-kappa B,
pubmed-meshheading:12046064-Oxazoles,
pubmed-meshheading:12046064-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:12046064-Reactive Oxygen Species,
pubmed-meshheading:12046064-Stomach Neoplasms,
pubmed-meshheading:12046064-Tumor Cells, Cultured,
pubmed-meshheading:12046064-Tumor Suppressor Protein p53
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pubmed:year |
2002
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pubmed:articleTitle |
Changes of NF-kB, p53, Bcl-2 and caspase in apoptosis induced by JTE-522 in human gastric adenocarcinoma cell line AGS cells: role of reactive oxygen species.
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pubmed:affiliation |
Department of Pharmacology, Jinan University Pharmacy College, Guangzhou 510632, Guangdong, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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