Linked Life Data

1204219

Source:http://linkedlifedata.com/resource/pubmed/id/1204219

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1976-3-11
pubmed:abstractText
The acid proteinase and the peroxidase activity of peripheral leucocytes of respectively 12 and 13 patients suffering from Spielmeyer-Vogt's disease, alias Batten's disease, alias Stengel's disease was studied. Cathepsin D activity was found to be normal in the disease, but the cathepsin B activity was decreased by 24 percent. However, the decrease was insignificant. The peroxidase assay was made using Guajacol as well as p-phenylenediamine as substrate. When the assay was performed with p-phenylenediamine, the enzymic activities were significantly decreased (p less than or equal to 1%) compared to the activity of normal control leucocytes. Assaying peroxidase activity by means of Guajacol revealed a non-significant difference between the two groups. The data obtained indicate the syndrome under study to be due to hampered peroxidase activity. The defect found explains the occurrence of lipofuchsin in the nervous system previously demonstrated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0009-8981
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
283-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Acid proteinase and peroxidase activity in spielmeyer-Vogt's syndrome (Batten's syndrome-Stengel's syndrome).
pubmed:publicationType
Journal Article, Comparative Study