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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2002-5-31
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pubmed:abstractText |
Alveolar rhabdomyosarcoma (ARMS) is an aggressive soft tissue malignancy of children and adolescents. Most ARMS patients express PAX3-FKHR or PAX7-FKHR gene fusions resulting from t(2;13) or t(1;13) translocations, respectively. We wished to confirm the diagnostic specificity of gene fusion detection in a large cohort of RMS patients and to evaluate whether these alterations influence clinical outcome in ARMS.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/FOXO1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Forkhead Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PAX3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/PAX7 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/PAX7 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Paired Box Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Pax3 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Markers, Biological
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0732-183X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2672-9
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pubmed:dateRevised |
2008-5-6
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pubmed:meshHeading |
pubmed-meshheading:12039929-Adolescent,
pubmed-meshheading:12039929-Child,
pubmed-meshheading:12039929-DNA-Binding Proteins,
pubmed-meshheading:12039929-Forkhead Transcription Factors,
pubmed-meshheading:12039929-Homeodomain Proteins,
pubmed-meshheading:12039929-Humans,
pubmed-meshheading:12039929-Multivariate Analysis,
pubmed-meshheading:12039929-Neoplasm Metastasis,
pubmed-meshheading:12039929-PAX7 Transcription Factor,
pubmed-meshheading:12039929-Paired Box Transcription Factors,
pubmed-meshheading:12039929-Prognosis,
pubmed-meshheading:12039929-Proportional Hazards Models,
pubmed-meshheading:12039929-RNA, Neoplasm,
pubmed-meshheading:12039929-Rhabdomyosarcoma, Alveolar,
pubmed-meshheading:12039929-Sensitivity and Specificity,
pubmed-meshheading:12039929-Survival Rate,
pubmed-meshheading:12039929-Transcription Factors,
pubmed-meshheading:12039929-Translocation, Genetic,
pubmed-meshheading:12039929-Tumor Markers, Biological
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pubmed:year |
2002
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pubmed:articleTitle |
PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's oncology group.
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pubmed:affiliation |
Department of Pathology, Children's and Women's Hospital of British Columbia, Vancouver, British Columbia, Canada. psor@interchange.ubc.ca
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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