Linked Life Data

12039580

Source:http://linkedlifedata.com/resource/pubmed/id/12039580

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2002-5-31
pubmed:abstractText
Paclitaxel (PTX) was complexed with beta-cyclodextrin (1), 2,6-dimethyl-beta-cyclodextrin (2) and 2,3,6-trimethyl-beta-cyclodextrin (3). PTX-CYD complexes were characterized both at the solid and liquid states. Experimental findings are in agreement with molecular modeling analysis, which showed different PTX-CYD interaction as a function of macrocyle methylation. The complexation of PTX within the CYD cavity preserved its antitumoral activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0960-894X
pubmed:author
pubmed:issnType
Print
pubmed:day
17
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1637-41
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Preparation, characterization, molecular modeling and in vitro activity of paclitaxel-cyclodextrin complexes.
pubmed:affiliation
Department of Pharmacobiological Sciences, University Magna Graecia of Catanzaro, Complesso Ninì Barbieri, I-88021 Roccelletta di Borgia (CZ), Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't