Linked Life Data

12038996

Source:http://linkedlifedata.com/resource/pubmed/id/12038996

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2002-5-31
pubmed:abstractText
Considerable progress has been made in manipulating oxidative biotransformations using oxygenases. Substrate acceptance, catalytic activity, regioselectivity and stereoselectivity have been improved significantly by substrate engineering, enzyme engineering or biocatalyst screening. Preparative biotransformations have been carried out to synthesize useful pharmaceutical intermediates or chiral synthons on the gram to several-hundred-gram scale, by use of whole cells of wild type or recombinant strains. The synthetic application of oxygenases in vitro has been shown to be possible by enzymatic or electrochemical regeneration of NADH or NADPH.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1367-5931
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
136-44
pubmed:dateRevised
2009-8-25
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Oxidative biotransformations using oxygenases.
pubmed:affiliation
Institute of Biotechnology, ETH Zurich, Hoenggerberg, CH-8093, Zurich, Switzerland. zhi@biotech.biol.ethz.ch
pubmed:publicationType
Journal Article, Review