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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2002-5-24
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pubmed:abstractText |
We investigated if dendritic cells (DC), derived from patients suffering from chronic myeloid leukemia (CML) could be modified by recombinant replication-defective adenoviruses to express functional interleukin 2 (IL-2). Such modification might confer onto antigen-presenting cells the ability to stimulate expansion of effector cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
1465-3249
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
97-105
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:12028832-Adenoviridae,
pubmed-meshheading:12028832-Antigen Presentation,
pubmed-meshheading:12028832-Dendritic Cells,
pubmed-meshheading:12028832-Gene Transfer Techniques,
pubmed-meshheading:12028832-Genetic Vectors,
pubmed-meshheading:12028832-Immunotherapy,
pubmed-meshheading:12028832-Interferon-gamma,
pubmed-meshheading:12028832-Interleukin-2,
pubmed-meshheading:12028832-Leukemia, Myelogenous, Chronic, BCR-ABL Positive,
pubmed-meshheading:12028832-Recombination, Genetic,
pubmed-meshheading:12028832-Th1 Cells,
pubmed-meshheading:12028832-Tumor Cells, Cultured
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pubmed:year |
2001
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pubmed:articleTitle |
Transgenic interleukin 2 secreted by CML dendritic cells stimulates autologous T(H)1 T cells.
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pubmed:affiliation |
Stem Cell Laboratory, Mayo Clinic Cancer Center, Rochester, MN 55905, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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