rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2002-5-24
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pubmed:abstractText |
Recent evidence suggests that angiotensin II (Ang II) induces a variety of proinflammatory mediators including chemokines. Nuclear factor-kappaB (NF-kappaB) activation plays an important role in Ang II-mediated inflammation. The present study investigated which Ang II receptor subtype is involved in NF-kappaB activation. We focused particularly on the Ang II subtype 2 (AT2) receptor because we previously observed that Ang II-induction of the chemokine RANTES in vitro and in vivo is mediated through AT2 receptors.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/I-kappa B Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappaB inhibitor alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Angiotensin, Type 1,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Angiotensin, Type 2,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Angiotensin
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0085-2538
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1986-95
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pubmed:dateRevised |
2010-3-23
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pubmed:meshHeading |
pubmed-meshheading:12028439-Angiotensin II,
pubmed-meshheading:12028439-Animals,
pubmed-meshheading:12028439-COS Cells,
pubmed-meshheading:12028439-Cell Nucleus,
pubmed-meshheading:12028439-DNA-Binding Proteins,
pubmed-meshheading:12028439-Electrophoresis,
pubmed-meshheading:12028439-I-kappa B Proteins,
pubmed-meshheading:12028439-NF-kappa B,
pubmed-meshheading:12028439-PC12 Cells,
pubmed-meshheading:12028439-Rats,
pubmed-meshheading:12028439-Receptor, Angiotensin, Type 1,
pubmed-meshheading:12028439-Receptor, Angiotensin, Type 2,
pubmed-meshheading:12028439-Receptors, Angiotensin
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pubmed:year |
2002
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pubmed:articleTitle |
Angiotensin II activates nuclear transcription factor-kappaB through AT1 and AT2 receptors.
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pubmed:affiliation |
Division of Nephrology and Osteology, Department of Medicine, University of Hamburg, Hamburg, Germany. Wolf@uke.uni-hamburg.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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