Source:http://linkedlifedata.com/resource/pubmed/id/12027768
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2002-5-24
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pubmed:abstractText |
Our investigations on the discovery of novel natural metabolites using type II polyketide synthase gene probes (actI/III) yielded an unusual angucyclinone, oviedomycin (2), when applied to the oleandomycin (1) producer Streptomyces antibioticus ATCC11891. The novel natural product was produced using S. albus R(-)M(-) as a host strain, into which a cosmid containing the oviedomycin gene cluster was transformed. Its structure was elucidated by NMR spectroscopy and mass spectrometry.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
779-82
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12027768-Aminoglycosides,
pubmed-meshheading:12027768-Ethers, Cyclic,
pubmed-meshheading:12027768-Magnetic Resonance Spectroscopy,
pubmed-meshheading:12027768-Mass Spectrometry,
pubmed-meshheading:12027768-Molecular Structure,
pubmed-meshheading:12027768-Multienzyme Complexes,
pubmed-meshheading:12027768-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:12027768-Spectrophotometry, Ultraviolet,
pubmed-meshheading:12027768-Spectroscopy, Fourier Transform Infrared,
pubmed-meshheading:12027768-Streptomyces antibioticus
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pubmed:year |
2002
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pubmed:articleTitle |
Oviedomycin, an unusual angucyclinone encoded by genes of the oleandomycin-producer Streptomyces antibioticus ATCC11891.
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pubmed:affiliation |
Departamento de Biología Funcional e Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, 33006 Oviedo, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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