rdf:type |
|
lifeskim:mentions |
umls-concept:C0010453,
umls-concept:C0021469,
umls-concept:C0021760,
umls-concept:C0024880,
umls-concept:C0030685,
umls-concept:C0041633,
umls-concept:C0052762,
umls-concept:C0086418,
umls-concept:C0147080,
umls-concept:C0391871,
umls-concept:C0527189,
umls-concept:C0680255,
umls-concept:C1283071,
umls-concept:C1963578
|
pubmed:issue |
5
|
pubmed:dateCreated |
2002-5-24
|
pubmed:abstractText |
Mast cells are involved in early- and late-phase reactions by releasing vasoactive molecules, proteases, and cytokines. Certain histamine-1 receptor antagonists and other antiallergic drugs seem to inhibit the release of mediators from rat and human mast cells.
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pubmed:grant |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Allergic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Dibenzoxepins,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Mcpt6 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Phthalazines,
http://linkedlifedata.com/resource/pubmed/chemical/Serine Endopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/TPSB1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Tryptases,
http://linkedlifedata.com/resource/pubmed/chemical/azelastine,
http://linkedlifedata.com/resource/pubmed/chemical/olopatadine
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pubmed:status |
MEDLINE
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pubmed:month |
May
|
pubmed:issn |
1081-1206
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
88
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
501-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12027072-Anti-Allergic Agents,
pubmed-meshheading:12027072-Cells, Cultured,
pubmed-meshheading:12027072-Dibenzoxepins,
pubmed-meshheading:12027072-Dose-Response Relationship, Drug,
pubmed-meshheading:12027072-Fetal Blood,
pubmed-meshheading:12027072-Histamine Release,
pubmed-meshheading:12027072-Humans,
pubmed-meshheading:12027072-Interleukin-6,
pubmed-meshheading:12027072-Lymphocyte Activation,
pubmed-meshheading:12027072-Mast Cells,
pubmed-meshheading:12027072-Phthalazines,
pubmed-meshheading:12027072-Serine Endopeptidases,
pubmed-meshheading:12027072-Tryptases
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pubmed:year |
2002
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pubmed:articleTitle |
Azelastine is more potent than olopatadine n inhibiting interleukin-6 and tryptase release from human umbilical cord blood-derived cultured mast cells.
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pubmed:affiliation |
Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and New England Medical Center, Boston, Massachusetts 02111, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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