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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2002-5-22
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pubmed:abstractText |
Hypersecretion of corticotropin-releasing hormone (CRH) in the brain has been implicated in stress-related human pathologies. We developed a transgenic mouse line overexpressing CRH (CRH-OE) exclusively in neural tissues to assess the effect of long-term CRH overproduction on regulation of the hypothalamic-pituitary-adrenal (HPA) axis.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jun
|
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pubmed:issn |
0006-3223
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
51
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
875-81
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:12022960-Adrenocorticotropic Hormone,
pubmed-meshheading:12022960-Animals,
pubmed-meshheading:12022960-Corticotropin-Releasing Hormone,
pubmed-meshheading:12022960-Gene Expression Regulation,
pubmed-meshheading:12022960-Genotype,
pubmed-meshheading:12022960-Hypothalamo-Hypophyseal System,
pubmed-meshheading:12022960-Mice,
pubmed-meshheading:12022960-Mice, Transgenic,
pubmed-meshheading:12022960-Pituitary-Adrenal System,
pubmed-meshheading:12022960-Stress, Physiological
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|
pubmed:year |
2002
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|
pubmed:articleTitle |
HPA axis dysregulation in mice overexpressing corticotropin releasing hormone.
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pubmed:affiliation |
Department of Psychopharmacology, Utrecht University, Utrecht, The Netherlands.
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pubmed:publicationType |
Journal Article
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