Source:http://linkedlifedata.com/resource/pubmed/id/12021553
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2002-5-21
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pubmed:abstractText |
Many drugs are known to induce allergic reactions in the skin. The metabolic activation of drugs resulting in the formation of protein adducts is thought to be a first step in the induction of these allergic reactions. We postulated that dermal tissue might be a site of drug activation by cytochrome P450 (CYP) isozymes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1018-2438
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2002 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
127
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
333-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12021553-Cells, Cultured,
pubmed-meshheading:12021553-Cytochrome P-450 Enzyme System,
pubmed-meshheading:12021553-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:12021553-Humans,
pubmed-meshheading:12021553-Isoenzymes,
pubmed-meshheading:12021553-RNA, Messenger,
pubmed-meshheading:12021553-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12021553-Skin
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pubmed:year |
2002
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pubmed:articleTitle |
mRNA expression of multiple cytochrome p450 isozymes in four types of cultured skin cells.
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pubmed:affiliation |
Project Team for Pharmacogenetics, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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