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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
20
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pubmed:dateCreated |
2002-5-21
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pubmed:abstractText |
Atherosclerosis is a multifactorial disorder involving inflammatory processes. These responses are associated with robust activation of signaling cascades by diverse cell surface receptors in a variety of cell types. The processes that are involved in atherosclerosis would likely require intact Ras pathways, which play a key role in the control of cell growth, differentiation, and apoptosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E,
http://linkedlifedata.com/resource/pubmed/chemical/Autoantibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Fats,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Farnesol,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/Salicylic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Cell Adhesion Molecule-1,
http://linkedlifedata.com/resource/pubmed/chemical/farnesylthiosalicylic acid,
http://linkedlifedata.com/resource/pubmed/chemical/oxidized low density lipoprotein,
http://linkedlifedata.com/resource/pubmed/chemical/ras Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
21
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2416-22
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:12021230-Animals,
pubmed-meshheading:12021230-Aorta,
pubmed-meshheading:12021230-Apolipoproteins E,
pubmed-meshheading:12021230-Arteriosclerosis,
pubmed-meshheading:12021230-Autoantibodies,
pubmed-meshheading:12021230-Cell Division,
pubmed-meshheading:12021230-Cells, Cultured,
pubmed-meshheading:12021230-Cholesterol,
pubmed-meshheading:12021230-Dietary Fats,
pubmed-meshheading:12021230-Disease Models, Animal,
pubmed-meshheading:12021230-Enzyme Inhibitors,
pubmed-meshheading:12021230-Farnesol,
pubmed-meshheading:12021230-Injections, Intraperitoneal,
pubmed-meshheading:12021230-Lipoproteins, LDL,
pubmed-meshheading:12021230-Male,
pubmed-meshheading:12021230-Mice,
pubmed-meshheading:12021230-Mice, Inbred C57BL,
pubmed-meshheading:12021230-Mice, Knockout,
pubmed-meshheading:12021230-NF-kappa B,
pubmed-meshheading:12021230-Salicylic Acids,
pubmed-meshheading:12021230-Spleen,
pubmed-meshheading:12021230-Treatment Outcome,
pubmed-meshheading:12021230-Triglycerides,
pubmed-meshheading:12021230-Vascular Cell Adhesion Molecule-1,
pubmed-meshheading:12021230-ras Proteins
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pubmed:year |
2002
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pubmed:articleTitle |
Functional inhibition of Ras by S-trans,trans-farnesyl thiosalicylic acid attenuates atherosclerosis in apolipoprotein E knockout mice.
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pubmed:affiliation |
Department of Cardiology and the Cardiovascular Research Laboratory, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
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pubmed:publicationType |
Journal Article
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