|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2002-5-20
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|
pubmed:abstractText |
As one of the future strategies of advanced pulmonary hypertension, intrinsic prostacyclin drug delivery using gene therapy may be useful. We investigated whether transfer of the prostacyclin synthase gene into the liver could ameliorate monocrotaline-induced pulmonary hypertension in rats.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0022-5223
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
123
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
855-61
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:12019369-Animals,
pubmed-meshheading:12019369-Blotting, Western,
pubmed-meshheading:12019369-Cytochrome P-450 Enzyme System,
pubmed-meshheading:12019369-Disease Models, Animal,
pubmed-meshheading:12019369-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:12019369-Gene Therapy,
pubmed-meshheading:12019369-Gene Transfer Techniques,
pubmed-meshheading:12019369-Hypertension, Pulmonary,
pubmed-meshheading:12019369-Immunohistochemistry,
pubmed-meshheading:12019369-Intramolecular Oxidoreductases,
pubmed-meshheading:12019369-Liver,
pubmed-meshheading:12019369-Lung,
pubmed-meshheading:12019369-Male,
pubmed-meshheading:12019369-Rats,
pubmed-meshheading:12019369-Rats, Sprague-Dawley,
pubmed-meshheading:12019369-Reference Values,
pubmed-meshheading:12019369-Statistics, Nonparametric,
pubmed-meshheading:12019369-Survival Rate,
pubmed-meshheading:12019369-Treatment Outcome
|
|
pubmed:year |
2002
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|
pubmed:articleTitle |
Gene transfer of human prostacyclin synthase into the liver is effective for the treatment of pulmonary hypertension in rats.
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|
pubmed:affiliation |
Division of Cardiovascular Surgery, Department of Surgery, Osaka University Graduate School of Medicine, Japan.
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|
pubmed:publicationType |
Journal Article,
Comparative Study
|
