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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1976-3-1
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pubmed:abstractText |
In order to elucidate the relationship between dopaminergic and serotoninergic mechanisms in regulating secretion of human growth hormone (hGH), the effect of cyproheptadine, an antiserotoninergic agent, on l-DOPA-induced hGH secretion was studied in normal subjects. Oral administration of 500 mg of l-DOPA caused a rise in plasma hGH in 6 of 7 subjects studied. This rise in plasma hGH was significantly blunted by the intravenous infusion of 5 mg of cyproheptadine. These results suggest the close relationship between dopamine and serotonin in the control of hGH secretion.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
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pubmed:issn |
0013-7219
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
22
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
357-60
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1201741-Adult,
pubmed-meshheading:1201741-Cyproheptadine,
pubmed-meshheading:1201741-Dihydroxyphenylalanine,
pubmed-meshheading:1201741-Growth Hormone,
pubmed-meshheading:1201741-Humans,
pubmed-meshheading:1201741-Male,
pubmed-meshheading:1201741-Pituitary Gland,
pubmed-meshheading:1201741-Pituitary Gland, Anterior
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pubmed:year |
1975
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pubmed:articleTitle |
Suppressive effect of cyproheptadine on L-DOPA-induced growth hormone release in man.
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pubmed:publicationType |
Journal Article
|