|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003320,
umls-concept:C0007634,
umls-concept:C0011306,
umls-concept:C0017638,
umls-concept:C0026336,
umls-concept:C0042210,
umls-concept:C0162638,
umls-concept:C0349661,
umls-concept:C0449416,
umls-concept:C0679199,
umls-concept:C1704419,
umls-concept:C1999230
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|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2002-5-17
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|
pubmed:abstractText |
On the basis of recent studies indicating that tumoral apoptotic bodies may provide a potent source of antigen for delivery to antigen-presenting cells, as well as observations that signal transduction modulation may constitute a promising approach for inducing glioma cell apoptosis, we explored the efficacy of vaccination with glioma apoptotic body-pulsed dendritic cells (DCs) for inhibiting tumor growth in the syngeneic 9L glioma/Fischer rat model.
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pubmed:grant |
|
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0148-396X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
50
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1327-34; discussion 1334-5
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|
pubmed:dateRevised |
2007-11-14
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|
pubmed:meshHeading |
pubmed-meshheading:12015852-Alkaloids,
pubmed-meshheading:12015852-Animals,
pubmed-meshheading:12015852-Antigens, Neoplasm,
pubmed-meshheading:12015852-Apoptosis,
pubmed-meshheading:12015852-Brain Neoplasms,
pubmed-meshheading:12015852-Cancer Vaccines,
pubmed-meshheading:12015852-Cell Communication,
pubmed-meshheading:12015852-Dendritic Cells,
pubmed-meshheading:12015852-Drug Administration Schedule,
pubmed-meshheading:12015852-Enzyme Inhibitors,
pubmed-meshheading:12015852-Glioma,
pubmed-meshheading:12015852-Gliosarcoma,
pubmed-meshheading:12015852-Rats,
pubmed-meshheading:12015852-Staurosporine,
pubmed-meshheading:12015852-Tumor Cells, Cultured,
pubmed-meshheading:12015852-Vaccination
|
|
pubmed:year |
2002
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|
pubmed:articleTitle |
7-Hydroxystaurosporine-induced apoptosis in 9L glioma cells provides an effective antigen source for dendritic cells and yields a potent vaccine strategy in an intracranial glioma model.
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|
pubmed:affiliation |
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pennsylvania, USA.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
