Source:http://linkedlifedata.com/resource/pubmed/id/12015841
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2002-5-17
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pubmed:abstractText |
Prognoses of pediatric high-grade gliomas are unpredictable, even when clinical and histological factors are taken into account. In preliminary studies with an institutional cohort of pediatric high-grade gliomas, we observed a strong association between outcome and proliferation index, as assessed by immunolabeling with the MIB-1 antibody. To determine whether this marker could provide prognostically useful information independent of tumor histology, we examined the prognostic usefulness of this marker in the multi-institutional cohort of Children's Cancer Group Study 945, the largest group of childhood high-grade gliomas analyzed to date.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0148-396X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1238-44; discussion 1244-5
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12015841-Antigens, Nuclear,
pubmed-meshheading:12015841-Astrocytoma,
pubmed-meshheading:12015841-Brain Neoplasms,
pubmed-meshheading:12015841-Cell Division,
pubmed-meshheading:12015841-Child, Preschool,
pubmed-meshheading:12015841-Cohort Studies,
pubmed-meshheading:12015841-Glioblastoma,
pubmed-meshheading:12015841-Glioma,
pubmed-meshheading:12015841-Humans,
pubmed-meshheading:12015841-Ki-67 Antigen,
pubmed-meshheading:12015841-Nuclear Proteins,
pubmed-meshheading:12015841-Prognosis,
pubmed-meshheading:12015841-Single-Blind Method,
pubmed-meshheading:12015841-Survival Analysis
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pubmed:year |
2002
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pubmed:articleTitle |
Impact of proliferation index on outcome in childhood malignant gliomas: results in a multi-institutional cohort.
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pubmed:affiliation |
Departments of Neurosurgery, University of Pittsburgh Medical Center and the Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA. Ian.Pollack@chp.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Multicenter Study
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