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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2002-5-23
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pubmed:abstractText |
The Jak/Stat signaling pathway transmits signals from many cytokines and growth factor receptors to target genes in the nucleus. Constitutive activation of Stat-3 recently has been observed in many tumor cells, and dysregulation of the Stat signaling pathway has been proposed to be implicated in malignant transformation. In the current study for the first time to the authors's knowledge, the expression of STAT-3 was analyzed in various stages and sites of squamous cell carcinoma of the head and neck (HNSCC).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2002 American Cancer Society.DOI 10.1002/cncr.10499
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2393-400
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12015764-Apoptosis,
pubmed-meshheading:12015764-Blotting, Western,
pubmed-meshheading:12015764-Carcinoma, Squamous Cell,
pubmed-meshheading:12015764-DNA-Binding Proteins,
pubmed-meshheading:12015764-Female,
pubmed-meshheading:12015764-Gene Expression,
pubmed-meshheading:12015764-Gene Expression Regulation,
pubmed-meshheading:12015764-Humans,
pubmed-meshheading:12015764-Male,
pubmed-meshheading:12015764-Middle Aged,
pubmed-meshheading:12015764-Mouth Neoplasms,
pubmed-meshheading:12015764-Precancerous Conditions,
pubmed-meshheading:12015764-RNA, Messenger,
pubmed-meshheading:12015764-STAT3 Transcription Factor,
pubmed-meshheading:12015764-Tobacco, Smokeless,
pubmed-meshheading:12015764-Trans-Activators
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pubmed:year |
2002
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pubmed:articleTitle |
Activation of Stat-3 as one of the early events in tobacco chewing-mediated oral carcinogenesis.
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pubmed:affiliation |
Molecular Oncology and Medical Biotechnology Division, Institute of Life Sciences, Chandrasekharpur, Bhubaneswar, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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