| pubmed-article:1201380 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1201380 | lifeskim:mentions | umls-concept:C0030956 | lld:lifeskim |
| pubmed-article:1201380 | lifeskim:mentions | umls-concept:C0205345 | lld:lifeskim |
| pubmed-article:1201380 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:1201380 | pubmed:dateCreated | 1976-3-1 | lld:pubmed |
| pubmed-article:1201380 | pubmed:abstractText | The pharmacological activity of two natural bombesin-like peptides, alytesin and litorin, and 25 related synthetic peptides has been compared to that of bombesin. 2 The minimum length of the amino acid chain required for the first appearance of bombesin-like effects was represented by the C-terminal heptapeptide, and the minimum length for maximal effects by the C-terminal nonapeptide. The latter possessed approximately the same activity as bombesin and may be considered a good substitute. 3 Both the tryptophan and histidine residues seemed to be essential for bombesin-like activity. 4 The C-terminal octapeptide was less active than either bombesin or the C-terminal nonapeptide and its action was more rapid in onset and less sustained. 5 Litorin apparently has an intermediate position between bombesin octapeptide and bombesin nonapeptide in the speed and duration of its effects. The relationship between structure and activity is discussed. | lld:pubmed |
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| pubmed-article:1201380 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:1201380 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1201380 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1201380 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:1201380 | pubmed:issn | 0007-1188 | lld:pubmed |
| pubmed-article:1201380 | pubmed:author | pubmed-author:NegriLL | lld:pubmed |
| pubmed-article:1201380 | pubmed:author | pubmed-author:MelchiorriPP | lld:pubmed |
| pubmed-article:1201380 | pubmed:author | pubmed-author:BroccardoMM | lld:pubmed |
| pubmed-article:1201380 | pubmed:author | pubmed-author:de... | lld:pubmed |
| pubmed-article:1201380 | pubmed:author | pubmed-author:Falconieri... | lld:pubmed |
| pubmed-article:1201380 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1201380 | pubmed:volume | 55 | lld:pubmed |
| pubmed-article:1201380 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1201380 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1201380 | pubmed:pagination | 221-7 | lld:pubmed |
| pubmed-article:1201380 | pubmed:dateRevised | 2010-9-7 | lld:pubmed |
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| pubmed-article:1201380 | pubmed:year | 1975 | lld:pubmed |
| pubmed-article:1201380 | pubmed:articleTitle | Relative potency of bombesin-like peptides. | lld:pubmed |
| pubmed-article:1201380 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1201380 | pubmed:publicationType | In Vitro | lld:pubmed |
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