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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1976-3-1
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pubmed:abstractText |
With thrombasthenic platelets, aggregation induced by ristocetin (R) and bovine fibrinogen (BF) is reversible, provided ATP is not added to the system. ADP inhibits BF and R induced aggregation, and when added after the onset of aggregation causes rapid disaggregation. ATP prevents these inhibitory and disaggregation effects of ADP. A mechanism is suggested whereby co-operative effects occur between receptors in the membranes of thrombasthenic platelets.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0007-1048
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1201247-Adenosine Diphosphate,
pubmed-meshheading:1201247-Adenosine Triphosphate,
pubmed-meshheading:1201247-Animals,
pubmed-meshheading:1201247-Blood Platelet Disorders,
pubmed-meshheading:1201247-Cattle,
pubmed-meshheading:1201247-Fibrinogen,
pubmed-meshheading:1201247-Humans,
pubmed-meshheading:1201247-Platelet Aggregation,
pubmed-meshheading:1201247-Ristocetin
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pubmed:year |
1975
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pubmed:articleTitle |
Effects of ADP and ATP on bovine fibrinogen- and ristocetin-induced platelet aggregation in Glanzmann's thrombasthenia.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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