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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1976-3-1
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pubmed:abstractText |
Human amniotic fluid has been shown to contain blood group i as well as I antigens. Crude extracts of amniotic fluids at 16-23 weeks of gestation were in general more active than those obtained at term. A pool of amniotic fluids which had A, B, H as well as I and i activity was fractionated with an insolubilized anti-I (Group 3 type) immunoadsorbent column. There was evidence for the occurrence of I and i determinants on macromolecules carrying A, B and H determinants, for the fraction specifically retained by the column was enriched by 50-60-fold in I and i activity and by at least 10-fold in A, B and H activity. In the fraction not retained by the column there remained the bulk of the A, B, H activity in addition to I activity of Group I type which is known to be distinct from the Group 3 determinant. With the aid of specific immunochemical fractionation procedures, human amniotic fluid should prove useful in structural studies of the several I and i determinants and of their relationship to other blood group determinants.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0007-1048
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
489-97
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1201230-ABO Blood-Group System,
pubmed-meshheading:1201230-Amniotic Fluid,
pubmed-meshheading:1201230-Blood Group Antigens,
pubmed-meshheading:1201230-Female,
pubmed-meshheading:1201230-Humans,
pubmed-meshheading:1201230-I Blood-Group System,
pubmed-meshheading:1201230-Isoantigens,
pubmed-meshheading:1201230-Pregnancy
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pubmed:year |
1975
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pubmed:articleTitle |
The blood group I and i antigens of amniotic fluid. I. Association of I and i antigens with blood group A, B and H antigens.
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pubmed:publicationType |
Journal Article
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