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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2002-5-15
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pubmed:abstractText |
A polymorphism (G to A transition) in intron 13 of the mitochondrial enzyme monoamine oxidase B (MAOB) gene may modify, alone or by interacting with the catechol-O-methyltransferase (COMT(LL)) genotype (low enzymatic activity), the risk of idiopathic PD. Also, the association between never smoking and PD risk may be present only in people with the MAOB G allele.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0028-3878
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1381-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12011284-Adult,
pubmed-meshheading:12011284-Aged,
pubmed-meshheading:12011284-Alleles,
pubmed-meshheading:12011284-Catechol O-Methyltransferase,
pubmed-meshheading:12011284-Cohort Studies,
pubmed-meshheading:12011284-European Continental Ancestry Group,
pubmed-meshheading:12011284-Female,
pubmed-meshheading:12011284-Follow-Up Studies,
pubmed-meshheading:12011284-Genetic Predisposition to Disease,
pubmed-meshheading:12011284-Genotype,
pubmed-meshheading:12011284-Health Personnel,
pubmed-meshheading:12011284-Humans,
pubmed-meshheading:12011284-Male,
pubmed-meshheading:12011284-Middle Aged,
pubmed-meshheading:12011284-Monoamine Oxidase,
pubmed-meshheading:12011284-Odds Ratio,
pubmed-meshheading:12011284-Parkinson Disease,
pubmed-meshheading:12011284-Polymorphism, Genetic,
pubmed-meshheading:12011284-Prospective Studies,
pubmed-meshheading:12011284-Questionnaires,
pubmed-meshheading:12011284-Risk Assessment,
pubmed-meshheading:12011284-Smoking,
pubmed-meshheading:12011284-United States
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pubmed:year |
2002
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pubmed:articleTitle |
MAOB intron 13 and COMT codon 158 polymorphisms, cigarette smoking, and the risk of PD.
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pubmed:affiliation |
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA. miguel_hernan@post.harvard.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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