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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0027651,
umls-concept:C0030274,
umls-concept:C0185117,
umls-concept:C0205312,
umls-concept:C0249880,
umls-concept:C0332281,
umls-concept:C0694891,
umls-concept:C1134719,
umls-concept:C1512936,
umls-concept:C1513712,
umls-concept:C1644197,
umls-concept:C2911684
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pubmed:issue |
6
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pubmed:dateCreated |
2002-5-15
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pubmed:abstractText |
Intraductal papillary mucinous tumours (IPMT) of the pancreas constitute a unique pathological entity with an overall incidence of associated invasive malignancy of 20%. The malignant potential of an individual IPMT cannot be accurately predicted. Preoperative estimation of the risk of associated invasive malignancy with IPMT would be of significant clinical benefit. As aberrations in cell cycle regulatory genes are associated with the progression of precursor pancreatic ductal lesions to invasive adenocarcinoma, we examined expression of key cell cycle regulatory genes in the cyclin D1/retinoblastoma pathway and the transforming growth factor beta/Smad4 signalling pathway in a cohort of patients with surgically resected IPMT.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-10096342,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-10398135,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-10522860,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-10537346,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-10555668,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-10587197,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-10593858,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-10623651,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-10658722,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-10854204,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-10878024,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-10980115,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-11751405,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-8104329,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-8740403,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-8910043,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-8939849,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9094170,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9134998,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9135016,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9242437,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9307274,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9358771,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9508208,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9563877,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9600293,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9671407,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9673562,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9738588,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9788631,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9815833,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9823374,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12010891-9951851
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CDKN1A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Cycle Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin D1,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor...,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Retinoblastoma Protein,
http://linkedlifedata.com/resource/pubmed/chemical/SMAD4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Smad4 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p53,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0017-5749
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
861-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:12010891-Humans,
pubmed-meshheading:12010891-Aged,
pubmed-meshheading:12010891-Aged, 80 and over,
pubmed-meshheading:12010891-Pancreatic Neoplasms,
pubmed-meshheading:12010891-Female,
pubmed-meshheading:12010891-Male,
pubmed-meshheading:12010891-Adenocarcinoma, Mucinous,
pubmed-meshheading:12010891-Middle Aged,
pubmed-meshheading:12010891-Tumor Cells, Cultured,
pubmed-meshheading:12010891-Carcinoma in Situ,
pubmed-meshheading:12010891-Immunohistochemistry,
pubmed-meshheading:12010891-DNA-Binding Proteins,
pubmed-meshheading:12010891-Tumor Suppressor Protein p53,
pubmed-meshheading:12010891-Trans-Activators
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