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pubmed:abstractText |
Dapsone (4,4-diaminodiphenylsulfone) is a sulfone antibiotic used in the treatment of leprosy, but dermatologists more commonly utilize its anti-inflammatory properties particularly directed against leukocytes to treat various bullous disorders, erythema nodosum, pyoderma gangrenosum, Sweet's syndrome, cutaneous vasculitis, and cutaneous forms of lupus erythematosus. The cutaneous manifestations of dermatomyositis are often resistant to antimalarial and immunosuppressive therapies.
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pubmed:affiliation |
Department of Dermatology, Univ. of Texas Southwestern Medical School, 5323 Harry Hines Boulevard, Dallas, TX 75390-9190, USA. jack.cohen@utsouthwestern.edu
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