Linked Life Data

1200722

Source:http://linkedlifedata.com/resource/pubmed/id/1200722

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1976-2-13
pubmed:abstractText
In five cases of dichlofenthion poisoning due to suicidal ingestions, unusual toxicologic features were encountered. Initial symptoms were mild or delayed and severe cholinergic crises did not appear until 40 to 48 hours after ingestion. Two patients died, and in the three survivors, cholinesterase symptoms persisted for five to 48 days. An almost total inhibiton of both cholinesterase enzymes continued in one patient for 66 days, and prolonged antidotal therapy was required. Residues of the intact pesticide were detected in fat after 54 days in one patient, and in the blood for 75 days in another patient. The partition coefficient of dichlofenthion in fat was 20 times greater than parathion, and exceeded only by leptophos. Considering the chemical and toxicologic properties of this compound, we postulated that the mechanism of protracted intoxication is a slow release from adipose reservoirs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0003-9896
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
608-13
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Human pesticide poisonings by a fat-soluble organophosphate insecticide.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Case Reports