12006548

Source:http://linkedlifedata.com/resource/pubmed/id/12006548

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0006826, umls-concept:C0042149, umls-concept:C0205312, umls-concept:C0242957, umls-concept:C0440743, umls-concept:C1514559
pubmed:issue	5
pubmed:dateCreated	2002-5-13
pubmed:abstractText	Uterine serous papillary carcinoma (USPC) is a highly aggressive variant of endometrial cancer and histologically similar to high-grade ovarian cancer. HER-2/neu, the transmembrane receptor encoded by the c-erbB2 gene, is overexpressed by immunohistology in approximately 25% of ovarian cancers. In this study, we have evaluated the expression of HER-2/neu in several fresh, established, paraffin-embedded, fixed USPCs. In addition, we have tested the sensitivity of USPC cells to Herceptin treatment.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized, http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal..., http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2, http://linkedlifedata.com/resource/pubmed/chemical/Receptor, erbB-2, http://linkedlifedata.com/resource/pubmed/chemical/rituximab, http://linkedlifedata.com/resource/pubmed/chemical/trastuzumab
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	1078-0432
pubmed:author	pubmed-author:AghaJamshedJ, pubmed-author:BelloneStefaniaS, pubmed-author:CannonMartin JMJ, pubmed-author:DunnDonnaD, pubmed-author:GokdenMuratM, pubmed-author:HutchinsLauraL, pubmed-author:O'BrienTimothyT, pubmed-author:PalmieriMichelaM, pubmed-author:ParhamGroesbeck PGP, pubmed-author:PecorelliSergioS, pubmed-author:RomanJuan JJJ, pubmed-author:SantinAlessandro DAD
pubmed:issnType	Print
pubmed:volume	8
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1271-9
pubmed:dateRevised	2011-11-17
pubmed:meshHeading	pubmed-meshheading:12006548-Aged, pubmed-meshheading:12006548-Antibodies, Monoclonal, pubmed-meshheading:12006548-Antibodies, Monoclonal, Humanized, pubmed-meshheading:12006548-Antibodies, Monoclonal, Murine-Derived, pubmed-meshheading:12006548-Antineoplastic Agents, pubmed-meshheading:12006548-Breast Neoplasms, pubmed-meshheading:12006548-Cell Division, pubmed-meshheading:12006548-Cystadenocarcinoma, Papillary, pubmed-meshheading:12006548-Cystadenocarcinoma, Serous, pubmed-meshheading:12006548-Female, pubmed-meshheading:12006548-Flow Cytometry, pubmed-meshheading:12006548-Humans, pubmed-meshheading:12006548-Immunohistochemistry, pubmed-meshheading:12006548-Interleukin-2, pubmed-meshheading:12006548-Killer Cells, Natural, pubmed-meshheading:12006548-Middle Aged, pubmed-meshheading:12006548-Neoplasm Staging, pubmed-meshheading:12006548-Ovarian Neoplasms, pubmed-meshheading:12006548-Receptor, erbB-2, pubmed-meshheading:12006548-Tumor Cells, Cultured, pubmed-meshheading:12006548-Uterine Neoplasms
pubmed:year	2002
pubmed:articleTitle	Overexpression of HER-2/neu in uterine serous papillary cancer.
pubmed:affiliation	Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Arkansas, Little Rock 72205-7199, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't