Source:http://linkedlifedata.com/resource/pubmed/id/12005165
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2002-5-13
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pubmed:abstractText |
To investigate the possible role of matrix metalloproteinase-7 in choroidal neovascularization associated with age-related macular degeneration, immunoelectron microscopy using ultrathin frozen sections and conventional transmission electron microscopy were performed in subfoveal fibrovascular membranes from patients with age-related macular degeneration. immunoelectron microscopy revealed that matrix metalloproteinase-7 was expressed within basal laminar deposits and amorphous materials around the retinal pigment epithelial cells. The results support a role for matrix metalloproteinase-7 in the development of choroidal neovascularization in age-related macular degeneration.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0022-0744
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
127-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12005165-Age Factors,
pubmed-meshheading:12005165-Aged,
pubmed-meshheading:12005165-Choroidal Neovascularization,
pubmed-meshheading:12005165-Humans,
pubmed-meshheading:12005165-Macular Degeneration,
pubmed-meshheading:12005165-Male,
pubmed-meshheading:12005165-Matrix Metalloproteinase 7,
pubmed-meshheading:12005165-Microscopy, Electron,
pubmed-meshheading:12005165-Microscopy, Immunoelectron,
pubmed-meshheading:12005165-Pigment Epithelium of Eye
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pubmed:year |
2002
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pubmed:articleTitle |
Role of matrix metalloproteinase-7 in angiogenesis associated with age-related macular degeneration.
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pubmed:affiliation |
Department of Anatomy, School of Medicine, Yokohama City University, Kanagawa, Japan. fyzma@med.yokohama-cu.ac.jp
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pubmed:publicationType |
Journal Article
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