Linked Life Data

12004236

Source:http://linkedlifedata.com/resource/pubmed/id/12004236

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Suppl
pubmed:dateCreated
2002-5-10
pubmed:abstractText
The endothelium is normally subjected to mechanical deformation resulting from shear stress and from strain associated with stretch of the vessel wall. These stimuli are detected by a mechanosensor that initiates a variety of signaling systems responsible for triggering the functional responses. The identity of the mechanosensor has not been established. This article discusses the different mechanisms of mechanosensing that have been proposed and reviews the literature with respect to signaling systems that are activated in response to stress and strain in endothelium.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0090-3493
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S198-206
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Endothelial responses to mechanical stress: where is the mechanosensor?
pubmed:affiliation
University of Chicago, Pulmonary and Critical Care Medicine, 5841 South Maryland Avenue, Chicago, IL, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review