Linked Life Data

11997689

Source:http://linkedlifedata.com/resource/pubmed/id/11997689

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2002-5-8
pubmed:abstractText
We studied the self-organization of memory-related activity through spike-timing-dependent plasticity (STDP). Relatively short time windows (approximately 10 ms) for the plasticity rule give rise to asynchronous persistent activity of low rates (20-30 Hz), which is typically observed in delay periods of working memory task. We demonstrate some network level effects on the activity regulation that cannot be addressed in single-neuron studies. For longer time windows (approximately 20 ms), the layered cell assemblies that propagate synchronized spikes (synfire chain) are self-organized. Synchronous spike propagation was suggested to underlie the precisely timed spikes in the monkey prefrontal cortex. The present results suggest that the two networks for sustained activity are different realizations of the same principle for synaptic wiring.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0959-4965
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
795-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Self-organization of memory activity through spike-timing-dependent plasticity.
pubmed:affiliation
Department of Information-Communication Engineering, Tamagawa University, 6-1-1 Tamagawagakuen, Machida, Tokyo 194-8610, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't