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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
16
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pubmed:dateCreated |
2002-5-8
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pubmed:abstractText |
The estrogen receptor-alpha (ER-alpha) IVS1-401 polymorphism identifies a group of women (approximately 20%) who have augmented effects of hormone replacement therapy (HRT) on levels of HDL cholesterol. This study sought to determine if this augmentation extends to HRT regulation of E-selectin and C-reactive protein (CRP) and to explore possible mechanisms by which this polymorphism might influence estrogen action.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:BleeckerEugene RER,
pubmed-author:BrosnihanK BridgetKB,
pubmed-author:HawkinsGregory AGA,
pubmed-author:HerringtonDavid MDM,
pubmed-author:HowardTimothy DTD,
pubmed-author:LiXiaolinX,
pubmed-author:McDonnellDonald PDP,
pubmed-author:MeyersDeborah ADA,
pubmed-author:ReboussinDavid MDM,
pubmed-author:XuJianfengJ,
pubmed-author:ZhengSiqun LSL
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pubmed:issnType |
Electronic
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pubmed:day |
23
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1879-82
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11997270-Base Sequence,
pubmed-meshheading:11997270-C-Reactive Protein,
pubmed-meshheading:11997270-Cardiovascular Diseases,
pubmed-meshheading:11997270-E-Selectin,
pubmed-meshheading:11997270-Estrogen Receptor alpha,
pubmed-meshheading:11997270-Estrogen Replacement Therapy,
pubmed-meshheading:11997270-Female,
pubmed-meshheading:11997270-Humans,
pubmed-meshheading:11997270-Middle Aged,
pubmed-meshheading:11997270-Polymorphism, Genetic,
pubmed-meshheading:11997270-Postmenopause,
pubmed-meshheading:11997270-Receptors, Estrogen,
pubmed-meshheading:11997270-Transcriptional Activation
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pubmed:year |
2002
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pubmed:articleTitle |
Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein.
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pubmed:affiliation |
Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1045, USA. kklein@wfubmc.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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