Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-5-8
pubmed:abstractText
Bovine colostrum is rich in antimicrobial substances and growth factors. The purpose of this open study was to examine and compare the interventory effects of daily use of bovine colostrum-containing oral hygiene products (CHP) on oral symptoms and findings in 20 patients with primary Sjogren's syndrome (pSS) and 20 age-matched patients with oral lichen planus (OLP). Objective oral measures and self-assessment of oral symptoms and general health were conducted before and after 90 days' use of CHP. The pSS patients had more systemic diseases, medication intake, oral dryness, poorer general health and lower salivary secretion than the OLP patients, who had the highest plaque index (PI) and the most mucosal soreness. Oral dryness and soreness were correlated to general health. In both patient groups. unstimulated whole saliva flow rate (UWS) had increased, PI and periodontal pocket depth (PPD) were reduced, and general health and oral dryness and soreness had improved after using CHP. A decrease in hyphae was found in candida smears from both groups and in blastospores in OLP smears. A reduction in the extension of the mucosal lesions was observed in 15 OLP patients. Results suggested beneficial effects of intervention with CHP on oral symptoms, general health, UWS, PI, PPD and candidal load in two patient groups--pSS and OLP--representing different oral symptomatology.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1432-6981
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
11-20
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:11996158-Adult, pubmed-meshheading:11996158-Aged, pubmed-meshheading:11996158-Animals, pubmed-meshheading:11996158-Anti-Infective Agents, pubmed-meshheading:11996158-Candidiasis, Oral, pubmed-meshheading:11996158-Case-Control Studies, pubmed-meshheading:11996158-Cattle, pubmed-meshheading:11996158-Colostrum, pubmed-meshheading:11996158-DMF Index, pubmed-meshheading:11996158-Dental Plaque Index, pubmed-meshheading:11996158-Dentifrices, pubmed-meshheading:11996158-Female, pubmed-meshheading:11996158-Follow-Up Studies, pubmed-meshheading:11996158-Growth Substances, pubmed-meshheading:11996158-Health Status, pubmed-meshheading:11996158-Humans, pubmed-meshheading:11996158-Lichen Planus, Oral, pubmed-meshheading:11996158-Male, pubmed-meshheading:11996158-Middle Aged, pubmed-meshheading:11996158-Mouthwashes, pubmed-meshheading:11996158-Periodontal Index, pubmed-meshheading:11996158-Periodontal Pocket, pubmed-meshheading:11996158-Protective Agents, pubmed-meshheading:11996158-Saliva, pubmed-meshheading:11996158-Sjogren's Syndrome, pubmed-meshheading:11996158-Statistics, Nonparametric, pubmed-meshheading:11996158-Xerostomia
pubmed:year
2002
pubmed:articleTitle
Oral findings in patients with primary Sjögren's syndrome and oral lichen planus--a preliminary study on the effects of bovine colostrum-containing oral hygiene products.
pubmed:affiliation
Department of Oral Physiology, Anatomy, Pathology and Medicine, School of Dentistry, University of Copenhagen, Denmark. amp@odont.ku.dk
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't