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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2002-5-6
pubmed:abstractText
This study describes the epidemiological association of 3 putative genes for virulence of uropathogenic Escherichia coli; uropathogenic specific protein (usp), a Vibrio cholerae zot gene homologue; IrgA homologue adhesin (iha), a nonhemagglutinating adhesin; and iroN(E. coli), a catechole siderophore receptor homologue. We compared the relative frequency in urinary tract infection (UTI) isolates (n=508), compared with non-UTI isolates (n=416). iroN(E. coli) occurred 2.1-3.6 times more frequently in UTI isolates than in rectal isolates (P=1.1x10-18 to P=2.7x10-5) and was associated with several uropathogenic virulence genes found on pathogenicity islands. usp occurred more frequently in isolates from patients with pyelonephritis (P=3.6x10-9), in periurethral isolates (P=.001), and in isolates from patients with UTI who were aged 40-65 years (P=.004), when compared with the rectal isolates; iha was not associated with UTI in this study.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-1899
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
185
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1521-4
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:11992291-Adolescent, pubmed-meshheading:11992291-Adult, pubmed-meshheading:11992291-Aged, pubmed-meshheading:11992291-Bacterial Proteins, pubmed-meshheading:11992291-Escherichia coli, pubmed-meshheading:11992291-Escherichia coli Infections, pubmed-meshheading:11992291-Escherichia coli Proteins, pubmed-meshheading:11992291-Female, pubmed-meshheading:11992291-Finland, pubmed-meshheading:11992291-Genes, Bacterial, pubmed-meshheading:11992291-Humans, pubmed-meshheading:11992291-Middle Aged, pubmed-meshheading:11992291-Odds Ratio, pubmed-meshheading:11992291-Prevalence, pubmed-meshheading:11992291-Pyelonephritis, pubmed-meshheading:11992291-Receptors, Cell Surface, pubmed-meshheading:11992291-Rectum, pubmed-meshheading:11992291-Urinary Tract Infections, pubmed-meshheading:11992291-Vibrio cholerae, pubmed-meshheading:11992291-Virulence
pubmed:year
2002
pubmed:articleTitle
Molecular epidemiology of 3 putative virulence genes for Escherichia coli urinary tract infection-usp, iha, and iroN(E. coli).
pubmed:affiliation
Department of Epidemiology, University of Michigan, School of Public Health, Ann Arbor, MI 48109, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.