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pubmed-article:11984515pubmed:abstractTextEradication of Helicobacter pylori leads to cure of gastric mucosa-associated lymphoid tissue (MALT) lymphoma in 75% of localized cases. However, prolonged follow-up is necessary to determine whether a lymphoma responds to therapy. In a small series of cases, we showed that t(11;18)(q21;q21)-positive MALT lymphomas failed to respond to H. pylori eradication. The present study aimed to verify this finding in a large cohort and confirm whether the translocation predicts the response of stage I(E) tumors, for which clinical staging has little prognostic value.lld:pubmed
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pubmed-article:11984515pubmed:articleTitleT(11;18) is a marker for all stage gastric MALT lymphomas that will not respond to H. pylori eradication.lld:pubmed
pubmed-article:11984515pubmed:affiliationDepartment of Histopathology, University College London, London, England.lld:pubmed
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