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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2002-5-1
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pubmed:abstractText |
Eradication of Helicobacter pylori leads to cure of gastric mucosa-associated lymphoid tissue (MALT) lymphoma in 75% of localized cases. However, prolonged follow-up is necessary to determine whether a lymphoma responds to therapy. In a small series of cases, we showed that t(11;18)(q21;q21)-positive MALT lymphomas failed to respond to H. pylori eradication. The present study aimed to verify this finding in a large cohort and confirm whether the translocation predicts the response of stage I(E) tumors, for which clinical staging has little prognostic value.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:BootHenkH,
pubmed-author:CalettiGiancarloG,
pubmed-author:De JongDaphneD,
pubmed-author:DoganAhmetA,
pubmed-author:DuMing-QingMQ,
pubmed-author:ElenaSabattiniS,
pubmed-author:HamoudiRifat ARA,
pubmed-author:IsaacsonPeter GPG,
pubmed-author:LavergneAnneA,
pubmed-author:LiuHongxiangH,
pubmed-author:MolinaThierryT,
pubmed-author:NeubauerAndreasA,
pubmed-author:PileriStefanoS,
pubmed-author:Ruskone-FourmestrauxAgnesA,
pubmed-author:StolteManfredM,
pubmed-author:TaalBabs GBG,
pubmed-author:ThiedeChristianC,
pubmed-author:ToglianiThomasT,
pubmed-author:WündischThomasT,
pubmed-author:YeHongtaoH,
pubmed-author:ZinzaniPier LuigiPL
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pubmed:issnType |
Print
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pubmed:volume |
122
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1286-94
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11984515-Adult,
pubmed-meshheading:11984515-Aged,
pubmed-meshheading:11984515-Aged, 80 and over,
pubmed-meshheading:11984515-Chromosomes, Human, Pair 11,
pubmed-meshheading:11984515-Chromosomes, Human, Pair 18,
pubmed-meshheading:11984515-Female,
pubmed-meshheading:11984515-Helicobacter Infections,
pubmed-meshheading:11984515-Helicobacter pylori,
pubmed-meshheading:11984515-Humans,
pubmed-meshheading:11984515-Lymphoma, B-Cell, Marginal Zone,
pubmed-meshheading:11984515-Male,
pubmed-meshheading:11984515-Middle Aged,
pubmed-meshheading:11984515-Neoplasm Staging,
pubmed-meshheading:11984515-Oncogene Proteins, Fusion,
pubmed-meshheading:11984515-Stomach Neoplasms,
pubmed-meshheading:11984515-Translocation, Genetic
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pubmed:year |
2002
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pubmed:articleTitle |
T(11;18) is a marker for all stage gastric MALT lymphomas that will not respond to H. pylori eradication.
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pubmed:affiliation |
Department of Histopathology, University College London, London, England.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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